IN ONE LINE
Glycolic acid is the smallest and most penetrating alpha hydroxy acid (AHA), exfoliating the skin's surface to reveal brighter, smoother skin and stimulate collagen over time.
Glycolic acid is a chemical exfoliant derived from sugarcane. As the smallest AHA molecule, it penetrates more deeply than other alpha hydroxy acids, making it the most potent — and the most likely to cause irritation if misused. It works by breaking the bonds between dead skin cells on the surface, allowing them to shed more quickly and revealing the fresher, brighter cells underneath. With regular use, it also signals fibroblasts to produce more collagen.
The key to glycolic acid is concentration and pH. At 5–10%, it's an effective leave-on exfoliant for home use; 20–70% is reserved for professional peels. Lower pH formulas (around 3–4) are more active. Many products balance efficacy with a less aggressive pH to minimize irritation, which is a reasonable trade-off. If you're new to exfoliating acids, starting with lactic acid — a gentler AHA — before moving to glycolic is often recommended.
How to use it
Apply leave-on glycolic acid 2–3 evenings per week, on clean skin before other serums. A cotton pad or direct application both work. There's no need to rinse off leave-on formulas — the buffered concentration is designed to work overnight. Follow with moisturizer.
Glycolic acid significantly increases UV sensitivity, so morning SPF is non-negotiable when using it. Don't layer it with retinol or other acids the same night. Many dermatologists recommend a simple rotation: glycolic acid one evening, retinol the next. Start once a week if you're new to AHAs and increase based on how your skin responds.
Check your products for glycolic acid.
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